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Image credit: Alison Burke, JAMA, 2005;294(20):2660
Image credit: http://www.medicalnewstoday.com/articles/285666.php
WHERE can you find HSCs?
Red Bone Marrow
Liver
Spleen
Umbilical Cord Blood
Placenta
Image credit: http://www.siumed.edu/~dking2/erg/placenta.htm
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HSCs are found in the red bone marrow of adults, and a small number of them are found in spleen and liver.
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They are also found in umbilical cord blood and placenta.
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A stem cell niche is where the stem cells reside, and it is a stable environment for stem cells.
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Regulation of HSC function relies on specialized cells and factors in the HSC niches.
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The condition of the niches is related to stem cell diseases.
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