Image credit: C. Blanpain, V. Horsley, E. Fuchs, Epithelial stem cells: turning over new leaves, Cell, 128 (2007), p. 445.
Image credit: C. Blanpain, V. Horsley, E. Fuchs, Epithelial stem cells: turning over new leaves, Cell, 128 (2007), p. 445.
HOW can ESCs help us?
Regenerating the Eye's Cornea
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ESCs are isolated from a biopsy of the other eye and allowed 100% recover of vision (middle)
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Microscope image (right) shows normal tissue organization after recovery
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Epithelial sheet from human keratinocytes (skin cells) grown on a fibrin matrix is shown on the left
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Patient's skin heals 3.5 years after the transplant
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Microscope image (right) shows that layers and structure of the epidermis look normal
Skin Regeneration
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ESCs are used to treat patient with alkali burns and scarring in the cornea of the eye (left)
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Epithelial sheets (2nd image) are used to treat patients with burns over 95% of his body
